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    Abstract

An Assessment of the Endotoxin Contents of Natural Rubber Latex Medical Gloves
A. Ikram and M.Y. Amir-Hashim

The endotoxin levels of Malaysian Natural Rubber (NR) latex medical gloves were determined by a kinetic turbidimetric Limulus Amoebocyte Lysate (LAL) assay. The samples evaluated were 39 pairs of sterilised surgical gloves from 10 commercially-available brands and 21 pairs of non-sterilised examination gloves from 8 brands. The endotoxin concentrations ranged from 3.2 to 114.1 EU/glove pair for surgical gloves and from < 8.4 to 9,632 EU/glove pair for the examination gloves. In the case of surgical gloves, 72% had endotoxin activity below the specified FDA standard of 20 EU/device, while in the case of the non-sterilised examination gloves, only 38% had values below the specified level. There was no correlation between endotoxin concentrations and the presence of glove powders in the present study.

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