Abstract - Cell Adhesion on Natural Rubber Latex Films: Influence of Surface Properties


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	Publications of MRB Latest Publications MRB Digest Journal of Rubber Research 3^rd Qtr 2008 Vol 11(3) 2^nd Qtr 2008 Vol 11(2) 1^st Qtr 2008 Vol 11(1) 4^th Qtr 2007 Vol 10(4) 3^rd Qtr 2007 Vol 10(3) 2^nd Qtr 2007 Vol 10(2) 1^st Qtr 2007 Vol 10(1) 1^st Qtr 2006 Vol 9(1) 2^nd Qtr 2006 Vol 9(2) 3^rd Qtr 2006 Vol 9(3) 4^th Qtr 2006 Vol 9(4) Submit paper/article Order Form	Abstract Cell Adhesion on Natural Rubber Latex Films: Influence of Surface Properties Adhesion, proliferation and spreading of cells on polymeric surfaces are regulated by the various surface properties of substrates, and cell responses are often indicative of their biocompatibility nature. Three differently prevulcanised natural rubber latexes i.e. irradiated (IR), peroxide (PX) and sulphur (SPV) vulcanised latexes and one non-vulcanised high ammoniated latex (HA) were examined for their wettability, surface microstructure and surface chemical composition. Influence of these surface properties on the cell activities of L929 fibroblasts was studied. Scanning electron microscopy showed that IR and PX supported greater cell activity than HA while SPV was inferior. Cell activity was enhanced on the rougher less hydrophobic and `cleaner' (i.e. surfaces with fewer chemicals) IR and PX surfaces. HA and SPV surfaces showed additional presence of a myriad of chemical elements not detected in IR or PX. SPV was particularly detrimental to cells, likely due to the distinct presence of zinc-related chemicals on its surface. It is apparent that the prevulcanisation process has imparted greater surface microstructure, and hydrophilicity to IR and PX surfaces, the probable reason for these two latex materials to be more superior for adhesion, proliferation and spreading of cells.
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