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Abstract
Impermeability of gloves and differently formulated NR
Latex films to ΦX174
The permeability of gloves and differently
formulated NR latex films to a challenge surrogate virus, ΦX174 of diameter
27nm, was assessed by a newly-developed method which could detect holes
greater than or equal to 2 µm. Samples from chlorinated and copolymerised
natural rubber gloves and gloves with different extractable protein contents
were found to be impermeable to the virus even when stretched 9X their original
areas. Similar results were obtained with samples from nitrile and vinyl
gloves. The integrities of the latex films were not affected when the films
were of different high-ammoniated latex concentrate sources, different levels
of non-rubber constituents, different curing systems, different moduli or
different leaching protocols. The films maintained their barrier properties
even after being aged at 70°C for 7 or 14 days. These clearly showed that
stretched latex films were not porous. Furthermore, impermeability to a
small virus such as ΦX174 indicated that the films could also be impervious
to human viruses such as hepatitis B or C viruses, human immunodeficiency
virus, herpes simplex virus and cytomegalovirus which are up to five times
bigger than ΦX174.
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